An Investigation into the Effects of Ubiquinone on Inflammation, Diabetic Myopathy and Endotheliopathy, and CBC Parameters in Diabetic Rats

Oxidative stress and inflammation are connected to the development of metabolic disorders, such as diabetes. Diabetic-related oxidative is caused by overproduction oxidative-free radicals, which have been implicated in mechanism damage tissues. Our study aimed investigate effects ubiquinone treatment on serum indicators (malondialdehyde (MDA)), (interleukin 6 (IL-6)), vascular homeostasis (nitric oxide (NO)), myopathy (myoglobin (MB)) addition measuring blood components parameters streptozotocin-induced diabetic rats. Rats were separated into three groups; negative control group (N), (D), ubiquinone-treated (T). After 21 days, samples taken evaluate fasting glucose (FBG), MDA, IL-6, NO, MB, hematological parameters. In hyperglycemic rats, levels FBG MB significantly increased, while NO decreased. Hyperglycemic condition lowered count WBC (P = 0.0098) but insignificantly decreased values platelets RBC. Ubiquinone reduced glucose, rats raised levels. The 0.648), RBC 0.001), 0.398) insignificant, only minor variations platelet observed. data support that supplementation could reduce proinflammation, stress, markers elevate current indicates may positively impact complications; however, additional research required determine its therapeutic benefit when added standard diabetes treatment.